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A thread that has run through my various rants on this blog, usually more implicitly than explicitly, has been blame. Who or what is to blame for something undesirable? Blame is another name for causation (of a negative outcome). As conscious beings we’re drawn to find that causation and attribute it to agents, be they gods/spirits/the universe, governments, corporations, CEOs, supervisors, friends or ourselves. In my mid-forties I’ve become better at watching myself for situations involving blame/causation and pause when entering them, because everyone’s unconscious bias often is to seek very simple scenarios of blame. But, much as we’re trained as scientists to find parsimonious conclusions, Occam’s razor can balance a very complex scenario on its knife-edge when reality is indeed very complex. And the point of this post is to explore how that complexity is often very real, but that needn’t be stifling. That’s probably bloody obvious to everyone but maybe the exploration will be interesting—or at least, for me, cathartic.

Stomach-Churning Rating: 0/10- or blame me. I’m at best an amateur philosopher and psychologist!

I feel that a big part of my job as a responsible human, adult, parent, supervisor, colleague, scientist, etc. is to blame myself when I deserve it. “Responsible” encompasses that ability to attribute blame/causation correctly. I find that blaming myself comes easier now that I’m battle-scarred and wiser for it, and I am more able to watch for excessive self-blame and paralytic pummelling than I was when I was younger. Low self esteem makes it easier to find the simple solution that you’re entirely to blame, or that simply someone else is. Excessive self confidence/power makes it easier to deny personal culpability or hunker down until it blows over. Balance is hardest– and I fail all the time.

I’ve been in many situations, ranging from the more micro-scale (smaller, embarrassing/silly events) to more traumatic (e.g. long-term arguments, correction/retraction of papers), in which I’ve had to consider blame or something like it. Foremost in my mind are my health problems and personal relationships. I’ve explored some of those here before and there are others I’d love to write about publicly but, no.

Yet lately it seems that blame is everywhere; the “blame culture” we hear about. Watch the news and virtually every story is about blame. Blame is a symptom of an angry world. It can be informative (or even a fun game) to think over who/what is not blamed in those stories (a simpler narrative is convenient, or propaganda and/or paranoia). We should be looking inwards at those we don’t want to blame, too.

There are many ways to confront the issue of blame. On one side we can say “don’t sweat the small stuff—and it’s all small stuff”. I hate that shit. “Happy happy joy joy” and all that; Voltaire rotates in his crypt. To me, that attitude also means “existence is meaningless” and “we are utterly powerless and blameless”, which is in contradiction to my experience and philosophy. On another side we can try to micromanage everything around us (small and big stuff), dissecting all the levels of blame in every situation, and we’d go/be insane. A middle ground approach within this spectrum, as usual, is best. Don’t be ashamed of that blame; it’s a thing we can tame.

Purpose and meaning in existence are chosen based on the direction we want our life to go (and how our successors look back on it postmortem). We place blame on those causative agents that push us away from that vector, and credit those that aid us. The more neutral agents are harder to grasp (e.g. the indifference of the universe to our existence). Purpose comes from our consciousness — to me they are the same; although our purpose leaves a legacy that persists after consciousness departs. Consciousness arises gradually from the spectrum of life – a virus is somewhat alive but closer to a rock than we are in terms of its “purpose” (more mechanical, less choices to make), then as evolution added nervous systems and other bits to life, more choices and complexity piled on. Purpose could be said to exist throughout that spectrum, from “instinct” to “choice”, all of which involve some causation — and chance. Vast oversimplification here, yes, but please stay with me. I’m getting there.

To avoid the extreme ends of the blame spectrum, we have to pick our battles and choose what is right or wrong in our world view. Lately I’ve watched smaller-scale events like United’s awful treatment of a passenger (and inability to de-escalate, then terrible PR handling) and huge global events like the resurgence of anti-intellectualism/populism or the clusterf*@$ in Syria, and blame inevitably comes to mind. Those who had more power AND responsibility to amend these situations, like CEOs or politicians, often deserve more blame. But the more complex story is that blame can be spread around these situations, much as they rightly anger us.

On an even smaller scale, close to my own profession and direct experience, I read a story by a PhD supervisor that largely blamed their student for falling silent (“supervisor phobia”) and then having problems with their degree, while the supervisor “was too busy to notice for another six months.” That seemed to exhibit gross irresponsibility for apportionment of blame in a messy situation: the old-fashioned legacy of authoritative, hierarchical scientific culture when people ranging from the university, department, colleagues, supervisor and student were to blame. It’s also a learning opportunity for many of us, to see how a bad situation evolved and think about what could have been done differently—indeed, differently from what one participant judges post hoc.

The red flag of a silent student/staff member could mean many things: the person might be intimidated about poor progress– or they might have self-esteem sharing what is actually good progress, they might be totally inactive (too little training? Hard technical problems stopping them?), or more. The point is that time is vital and acting too late probably will only worsen the problem, adding more blame to the supervisor and upper echelons.

The overall, common-sense approach I’ve cultivated with figuring ways out of hard situations at work and elsewhere is to (1) watch for (potential) problems, (2) think them through – allowing for the conclusion to be that the situation is complex and requires a nuanced approach (e.g. openly accepting one’s own culpability, maybe not yet pointing fingers at others deserving blame), and then (3) take action to try to resolve them. “The system” (e.g. rules and regulations) may be part of the problem but it can also be part of the solution. Although the system’s carrot is far more pleasant to use than the stick, they are there for reasons, to be applied with empathy and patience. Being human, we can run out of those latter two things and their fuel levels need monitoring.

The hope is that, finally, action leads eventually to a better outcome with a lesson mutually learned and, eventually, greater peace of mind as we reconcile our worldview with reality. The distinct possibility, though, is that we can’t fix everything and sometimes we have to try to find contentment in an imperfect world. Some causes are mysterious and we might have to settle for that mystery. Or we can spiral into paranoia and conspiracy theories; all the rage today; which can be simple scenarios of blame or very elaborate ones. These scenarios deserve their own rational inspection for personal biases that lead toward them, and the desire for easy answers.

But we can still blame the fucked up shit, and that can be therapeutic. Even if we hold onto blame, we can forgive it. Maybe this holiday weekend is a good time to forgive someone that is blamed.

A Confuciusornis fossil; not the one from our study but prettier (more complete).

Today almost three years of collaboration come together in a publication that is a fun departure from my normal research, but also makes sense in light of it. Professor Baoyu Jiang from Nanjing University in China has been being working on the taphonomy of the Early Cretaceous Jehol biota from northeastern China (Manchuria) for a while, and he found a lovely Confuciusornis (early bird) fossil; one of thousands of them; from the volcanic pyroclastic flow-based lake deposits there.

Although at first glance the skeletal remains of that fossil are not fabulous compared with some other Confuciusornis, what makes this one lovely is that, on peering at it with multiple microscopic and other imaging techniques, he (and me, and a China-UK collaboration that grew over the years) found striking evidence of very well-preserved fossil soft tissues. Our paper reporting on these findings has gone live in Nature Communications so I can blog about it now.

Reference: Jiang, B., Zhao, T., Regnault, S., Edwards, N.P., Kohn, S.C., Li, Z., Wogelius, R.A., Benton, M., Hutchinson, J.R. 2017. Cellular preservation of musculoskeletal specializations in the Cretaceous bird Confuciusornis. Nature Communications 8:14779. doi: 10.1038/NCOMMS14779

Stomach-Churning Rating: 3/10; gooey, but fossil gooey, except for some colourful, gastrically-tolerable histology of bird tissue.

Front view of the ankle/foot of our specimen.

Back view of the ankle/foot of our specimen.

What has been fun about this collaboration is that, for one, it fits in perfectly with my prior work. Ever since my PhD thesis I’d been wondering about odd bones in the legs of birds, including a very puzzling and very, very neglected bit of bone called the tarsal sesamoid, on the outside of the upper end of the ankle joint. Furthermore, a tunnel of tissue called the tibial cartilage sits next to that sesamoid bone, and then across the ankle joint there is a bony prominence with grooves and tunnels that vary highly among bird species; that is called the hypotarsus. These structures are all known in living birds and, to a degree, in extinct fossil cousins. Our specimen seems to reveal an earlier stage in how these little features of bird ankles originated, which we concluded to be a step along the transition to the more crouched legs that modern birds have.

This study has also challenged me to broaden my horizons as a scientist. Although this was a big collaboration and thus we had several specialists to apply supercharged technological techniques to our fossil, I had to learn something about what all that meant. My kind colleagues helped me learn more about tissue histology, scanning electron microscopy, synchrotron mapping, FTIR and mass spectrometry and more. I won’t go through all of these techniques but there are some pretty pictures sprinkled here and in the paper, and a lot more detail in the paper for those who want the gory techno-detail. Basically we threw the kitchen sink of science at the fossil to crack open some of its secrets, and what we found inside was nifty.

Scanning electron micrograph image of probable tendon or ligament fibres (arrow) in cross-section, from near the ankle joint.

We found preserved cells and other parts of connective tissues including tendons and/or ligaments, fibrocartilage (the tougher kind) and articular cartilage (the softer joint-padding kind). That’s great, although not unique, but the kitchen sink also flushed out even more reductionist data: those tissues included some organic residues, including what appear to be bits of proteins (amino acids); particularly the collagen that makes up tendons.

Fibrocartilage (“fc”) from the ankle joint region.

Hopefully we’re right, and we included as much of the data as we could manage so that others can look at our findings. The specimen is crushed into nearly two dimensions, like all Jehol biota organisms, so its anatomy was hard to interpret but we think we got it right. All of the other kitchen-sinky tools have their own nuances and pitfalls but we did our best with a superb team of experts. We’ve had to wait 125 million years to uncover this specimen and a few more years to find out if we’ve looked at the right way is no greater test of patience.

I thank my coauthors, especially Baoyu Jiang for the kind invitation to participate and the very fun experience of collaborating. I think I’ll remember this study for a long time because, for me, it takes a step beyond just describing Another Case of Jaw-Dropping Fossilization (can you hear the hipsters recounting the excitement and cynicism of the 1990s when this all was dawning? I was there and maybe now I’m one of them). By combining all of those methods we learned new things about the palaeobiology of birds and the evolution of traits within birds. Confuciusornis, not shockingly, had ankles that should have functioned in ways intermediate between those of bog-standard non-avian theropods and modern birds.

Same anatomical regions in an extant bird as in the main fossil specimen. Left distal tibiotarsus (TT; below) and proximal tarsometatarsus (TMT; above) from an adult helmeted guineafowl (Numida meleagris) after formalin fixation. (from our paper’s Supp Info)

I’m hopeful that more synthesis of molecular/cellular, imaging, biomechanical and other tools (not to mention good old palaeontology and anatomy!) can wash away some more of this mystery. And it was fun to be a part of a study that adds to overwhelming evidence that was heretical ~25 years ago: some hardy biomolecules such as collagen and keratin can survive hundreds of millions of years, not just thousands. Pioneers such as Prof. Mary Schweitzer led the original charge that made reporting on discoveries like ours much easier today.

I know how the birds fly, how the fishes swim, how animals run. But there is the Dragon. I cannot tell how it mounts on the winds through the clouds and flies through heaven. Today I have seen the Dragon.“– Confucius, ca. 500 BCE.

Let’s finish with some images of a living bird’s ankle region, by co-author and PhD student Sophie Regnault. We considered these for inclusion in the paper but they didn’t fit quite right. I love them anyway so here they are:

Patchwork of histology slide images, from a guineafowl’s ankle (as per photo above). The numbered squares correspond to zoomed-in images below. The tibiotarsus is on the proximal end (bottom left); the tarsometatarsus is on the distal end (right side); and the enigmatic tarsal sesamoid is at the top. Magnification: 20x overall.

Region 1. nice (fibro)cartilage-bone inferface at ligament insertion.

Region 2: longitudinal slice through ligaments connecting the tibiotarsus to the tarsometatarsus across the ankle joint.

Region 3: front (bottom) of the tibiotarsus/upper ankle.

Region 4: tendon fibres in longitudinal section; on the back of the tibiotarsus. Some show mineralization into ossified tendons (“metaplasia”); another curious feature of modern birds.

Region 5: muscle attachment to the back of the upper tarsometatarsus bone. Small sesamoid fragment visible.

The early, hippo-like mammal Coryphodon. I didn’t know it had a patella but it does. From Yale Peabody Museum.

I’m not shy about my fondness for the patella (kneecap) of tetrapod vertebrates, and neither are the other members of RVC’s “Team Patella”. We’ve had a fun 3+ years studying these neglected bones, and today we’ve published a new study of them. Our attention has turned from our prior studies of bird and lepidosaur kneecaps to mammalian ones. Again, we’ve laid the groundwork for a lot of future work by focusing on (1) basic anatomy and (2) evolutionary history of these sesamoid bones, with a lot of synthesis of existing knowledge from the literature; including development and genetics. This particular paper is a sizeable monograph of the state of play in the perusal of patellae in placental and other synapsids. Here’s what we did and found, focusing mostly on bony (ossified) patellae because that allowed us to bring the fossil record better to bear on the problem.

Reference: Samuels, M., Regnault, S., Hutchinson, J.R. 2016. Evolution of the patellar sesamoid bone in mammals. PeerJ 5:e3103 https://doi.org/10.7717/peerj.3103

Stomach-Churning Rating: 1/10; bones and more bones.

The short version of the story is that mammals evolved bony kneecaps about five times, with marsupials gaining and losing them (maybe multiple times) whereas monotremes (platypus and echidna) and placentals (us and other mammals) didn’t do much once they gained them, and a couple of other fossil groups evolved patellae in apparent isolation.

Evolution of the patella in mammals: broad overview from our paper. Click to zoom in.

The marsupial case is the most fascinating one because they may have started with a fibrocartilaginous “patelloid” and then ossified that, then reduced it to a “patelloid” again and again or maybe even regained it. There needs to be a lot more study of this group to see if the standard tale that “just bandicoots and a few other oddballs have a bony patella” is true for the Metatheria (marsupials + extinct kin). And more study of the development of patellae in this group could help establish whether they truly do “regress” into fibrocartilage when they are “lost” in evolution, or if other, more flexible patterns exist, or even if some of the cases of apparent “loss” of a bony patella are actually instances of delayed ossification that only becomes evident in older adults. Our paper largely punts on these issues because of an absence of sufficient data, but we hope that it is inspiration for others to help carry the flag forward for this mystery.

The higgledy-piggledy evolution of a patella in Metatheria, including marsupials. Click to zoom in.

Some bats, too, do funky things with their kneecaps, analogous to the marsupial “patelloid” pattern, and that chiropteran pattern also is not well understood. Why do some bats such as Pteropus fruit bats “lose” their kneecaps whereas others don’t, and why do some bats and other species (e.g. various primates) seem to have an extra thing near their kneecaps often called a “suprapatella”? Kneecap geeks need to know.

The short-nosed bandicoot (marsupial) Isoodon, showing a nice bony patella as typifies this group. From Yale Peabody Museum.

Otherwise, once mammals evolved kneecaps they tended to keep them unless they lost their hindlimbs entirely (or nearly so). Witness the chunky patellae of early whales such as Pakicetus and join us in wondering why those chunks persisted. The evolutionary persistence of blocky bits of bone in the knees of various aquatic animals, especially foot-propelled diving birds, may help answer why, as the hindlimbs surely still played roles in swimming early in cetacean evolution. Ditto for sea cows (Sirenia) and other groups.

Early whale Ambulocetus, showing hefty kneecaps.

But I’m still left wondering why so many groups of land vertebrates (and aquatic ones, too) never turned parts of their knee extensor tendons into bone. We know a bit about the benefits of doing that, to add leverage to those joints that enables the knee muscles to act with dynamic gearing (becoming more forceful “low gear” or more speedy “high gear” in function). Non-avian (and most early avian/avialan) dinosaurs, crocodiles, turtles, amphibians, early mammal relatives, and almost all other known extinct lineages except for those noted above got by just fine without kneecaps, it seems, even in cases where a naïve biomechanist would expect them to be very handy, such as in giant dinosaurs.

A quoll, Dasyurus, with what is probably a fibrocartilaginous “patelloid”. From Yale Peabody Museum.

However, tendons don’t turn to bone unless the right stresses and strains are placed upon them, so maybe kneecaps are a “spandrel” or “exaptation” of sorts, to abuse Gould’s ghost, whose adaptive importance is overemphasized. Maybe that adaptive myopia overshadows a deeper ontogenetic story, of how tissues respond to their history of mechanical loading environment. It has been speculated that maybe (non-marsupial) mammals have broadly “genetically assimilated” their kneecaps, fixing them into semi-permanence in their genetic-developmental programmes, whereas in contrast the few studies of birds indicate more responsiveness and thus less assimilation/fixation. That “evo-devo-mechanics” story is what now fascinates me most and we’ve poked at this question a bit now, with some updates to come- watch this space! Regardless, whether an animal has a bony vs. more squishy soft tissue patella must have consequences for how the knee joint and muscles are loaded, so this kind of question is important.

Giant marsupial Diprotodon (at NHM London); to my knowledge, not known to have had kneecaps- why?

In the meantime, enjoy our latest contribution if it interests you. This paper came about when first author Dr. Mark Samuels emailed me in 2012, saying he’d read some of my old papers on the avian musculoskeletal system and was curious about the evolution of patellae in various lineages. Unlike many doctors and vets I’ve run into, he was deeply fascinated by the evolutionary and fossil components of patellae and how those relate to development, genetics and disorders of patellae. We got talking, found that we were kindred kneecap-spirits, and a collaboration serendipitously spun off from that, soon adding in Sophie. It was a blast!

‘Full fathom five thy father lies, of his bones are coral made. Those are pearls that were his eyes. Nothing of him that doth fade, but doth suffer a sea-change into something rich and strange.’

(Shakespeare’s The Tempest Act 1, Scene 2)

Stomach-Churning Rating: 1/10- this time, tame images.

Five years have passed on this blog now, and this year with them passed Freezersaurus (soon to leave RVC’s campus; sob!). Indeed, the blog has changed, via the tempests I’ve weathered in my own life, which I lamented in last year’s summary. Regardless, the blog has been visited this year more than in any prior year, with >101,000 visits– thanks!

This year I’ll keep my annual retrospective shorter than usual, as I’m feeling healthier and more energetic but less self-indulgent.

I still got to have fun, like this ComicCon in NOLA. So, some self-indulgence.

I still got to have fun, like this ComicCon in NOLA. So, some self-indulgence.

I began the past year by blogging about why I blog, and how I feel that in a way I (and others) have long been blogging even if it wasn’t called that, and how I don’t see science communication such as blogging or tweeting as something distinct from science itself. Reading back on that post, I find some themes there that emerge again and again throughout this year’s posts, such as valuing diversity (in its diverse forms) and curiosity.

Like this? So much more is here!

Like this you do? So much more here there is!

Never tired of elephant feet will I be!

Those introspective posts included one that is very close to my heart, about how I notice my own decline (some of it since reversed, but some still lingering) and feel grief. It wasn’t long after that post that I wrote more about my experience as an epileptic; what it’s like to have a seizure. Another, more science-focused (but still very human) one laid out my views on what my team’s principles are. Then I returned a few posts later with some reflection on how time passes (too quickly!) and with it come publications (I reviewed some of my team’s latest), among other changes as a person living as an academic. I wrote then that “I suspect I’ll look back on 2016 and see it as transformative, but it hasn’t been an easy year either, to say the least.” Yep. Spot on. I’ve started a big new grant which has been a huge challenge, and I’ve rediscovered my health and some of my old self with it, rekindling some passion and hope. Later, on USA’s Thanksgiving, I typed in some musings about my appreciation for diversity in the human world. Again, with thoughts of disturbing recent political/social trends weighing heavily on me, I celebrated how the Women’s March inspired me, and how that relates to the importance of curiosity and empathy.

He ain't goin' nowhere.

He ain’t goin’ nowhere.

But there was plenty of time here to talk about freezers and anatomy and research, too! We published a paper that I think I’ll long regard as one of our better ones, on using dynamic computer simulations to study how ostriches control their walking and running gaits with their muscles. Throughout 2016, we worked hard to get our anatomical research out there to the public in person. So I posted about our presentations at the Cheltenham Science Festival (including a public cheetah dissection, which was a huge hit!), and “Team Cat” did a dissection of another cheetah (all zoo mortalities) at the RVC for a well-attended joint event with UCL/Grant Museum on “Wild Cats Uncovered: movement evolves“. UCL’s PhD student (soon Dr.) Marcela Randau wrote a great guest post about our paper on how size and ecology relate to the shapes of backbones in cats, which tied in nicely with those big cat dissection presentations. I also ruminated about how scientists balance testing big questions vs. getting very accurate data, using the big question (in my and others’ research) about how much more slowly big animals can move relative to smaller ones as an example. As a final anatomical post this blog-year, I wrote about the biceps muscle, and people seemed to like that, so I will do more of those.

Whale humeral epiphysis (joint) turned into a sculpture with walrus ivory teeth, at Point Vicente Museum, LA.

Whale humeral epiphysis (joint) turned into a sculpture with walrus ivory teeth, at Point Vicente Museum, LA.

In addition to being open about my (and my team’s) thoughts, experiences, dissections and publications, we put a lot of effort this year into making our scientific and anatomical data public. My blog posts about our huuuuuge open datasets on crocodile and tuatara 3D scans exemplify a deluge of data that is going to keep coming out. We’re going to push very hard on this, including an effort to release old data from prior publications of mine. I’m thrilled that we can finally deliver on these things; it is a great feeling!

Yale Peabody Museum specimen YPM57100: ilium (hip bone) and vertebrae of the Triassic archosaur Poposaurus. More about this later!

Yale Peabody Museum specimen YPM57100: right ilium (hip bone) and vertebrae of the Triassic archosaur Poposaurus. More about this later!

We enter year 6 of this blog with a new (temporary, maybe) freezer, which we failed to reach a conclusion on naming. I’m sure you’re on tenterhooks awaiting the final decision. I have a bunch of ideas for some blog posts to come soon (really fun anatomical papers en route), and I always welcome guest posts so let me know if you want to do one! In the meantime, I sprinkled some images from my 2016-7 travels here in this post. With good health comes more ability to go do fun things that I’ve put off while recovering, so hopefully 2017-8 will provide some new images to share.

A sunny Sceloporus fence lizard seen in LA.

A sunny Sceloporus fence lizard seen in LA. Meanwhile, the UK awaits some sunshine…

I doth not protest too much, methinks– there have been some good times this past year, and ides of March be damned, I look forward to sharing more science here for year 6!

Nice GIF of the human biceps in action- By Niwadare - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=38718790

GIF of the human biceps (above) and its antagonist triceps (below) in action- By “Niwadare” – own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=38718790

Last year on Darwin Day I debuted “Better Know A Muscle” (BKAM), which was intended to be a series of posts focusing on one cool muscle at a time, and its anatomical, functional and evolutionary diversity and history. A year later, it’s another post on another muscle! Several dozen more muscles to go, so I’ve got my work cut out for me… But today: get ready to FLEX your myology knowledge! Our subject is Musculus biceps brachii; the “biceps” (“two-headed muscle of the arm”). Beloved of Arnie and anatomists alike, the biceps brachii is. Let’s get pumped up!

Stomach-Churning Rating: 7/10. Lots of meaty elbow flexion!

While the previous BKAM’s topic was a hindlimb muscle with a somewhat complex history (and some uncertainties), the biceps brachii is a forelimb muscle with a simpler, clearer history. Fish lack a biceps, just having simple fin ab/adductor muscles with little differentiation. Between fish and tetrapods (limb-bearing vertebrates), there was an explosion in the number of muscles; part of transforming fins into limbs; and the biceps is thenceforth evident in all known tetrapods in a readily identifiable anatomical form. In salamanders and their amphibian kin, there is a muscle usually called “humeroantebrachialis” that seems to be an undivided mass corresponding to the biceps brachii plus the brachialis (shorter humerus-to-elbow) muscle:

Most of the humerobrachialis muscle (purplish colour), in dorsal (top) view of the right forelimb of the fire salamander Salamandra salamandra (draft from unpublished work by my team).

Most of the humerobrachialis muscle (purplish colour), in dorsal (top) view of the right forelimb of the fire salamander Salamandra salamandra (draft from unpublished work by my team).

In all other tetrapods; the amniote group (reptiles, mammals, etc.); there is a separate biceps and brachialis, so these muscles split up from the ancestrally single “humeroantebrachialis” muscle sometime after the amphibian lineage diverged from the amniotes. And not much changed after then– the biceps is a relatively conservative muscle, in an evolutionary (not political!) sense. In amniote tetrapods that have a biceps, it develops as part of the ventral mass of the embryonic forelimb along with other muscles such as the shorter, humerus-originating brachialis, from which it diverges late in development (reinforcing that these two muscles are more recent evolutionary divergences, too).

Biceps brachialis or humerobrachialis, the “biceps group” tends to originate just in front of the shoulder (from the scapula/coracoid/pectoral girdle), running in front of (parallel to) the humerus. It usually forms of two closely linked heads (hence the “two heads” name), most obviously in mammals; one head is longer and comes from higher/deeper on the pectoral girdle, whereas the other is closer to the shoulder joint and thus is shorter. The two heads fuse as they cross the shoulder joint and we can then refer to them collectively as “the biceps”. It can be harder to see the longer vs. shorter heads of the biceps in non-mammals such as crocodiles, or they may be more or less fused/undifferentiated, but that’s just details of relatively minor evolutionary variation.

The biceps muscle then crosses in front of the elbow to insert mainly onto the radius (bone that connects your elbow to your wrist/thumb region) and somewhat to the ulna (“funny bone”) via various extra tendons, fascia and/or aponeuroses. The origin from the shoulder region tends to have a strong mark or bony process that identifies it, such as the coracoid process in most mammals (I know this well as I had my coracoid process surgically moved!). The insertion onto the radius tends to have a marked muscle scar (the radial tuberosity or a similar name), shared with the brachialis to some degree. A nice thing about the biceps is that, because it may leave clear tendinous marks on the skeleton, we sometimes can reconstruct how its attachments and path evolved (and any obvious specializations; even perhaps changes of functions if/when they happened).

Here are some biceps examples from the world of crocodiles:

Crocodile's right forelimb showing the huge pectoralis, and the biceps underlying it on the bottom right.

Crocodile’s right forelimb showing the huge pectoralis, and the biceps underlying it; on the bottom right (“BB”- click to embiceps it).

Crocodile left forelimb with biceps visible (

Crocodile left forelimb with biceps visible (“BB”) on the left.

Crocodile biceps muscle cut off, showing the proximal and distal tendons (and long parallel muscle fibres) for a typical amniote vertebrate.

Crocodile biceps muscle cut off, showing the proximal (to right) and distal (to left) tendons (and long parallel muscle fibres) for a typical amniote vertebrate.

What does the biceps muscle do? It flexes (draws forward) the shoulder joint/humerus, and does the same for the elbow/forearm while supinating it (i.e. rotating the radius around the ulna so that the palm faces upwards, in animals like us who can rotate those two bones around each other). In humans, which have had their biceps muscles studied by far the most extensively, we know for example that the biceps is most effective at flexing the elbow (e.g. lifting a dumbbell weight) when the elbow is moderately straight. These same general functions (shoulder and elbow flexion; with some supination) prevail across the biceps muscle of [almost; I am sure there are exceptions] all tetrapods, because the attachments and path of the biceps brachii are so conservative.

And this flexor function of the biceps brachii stands in contrast to our first BKAM muscle, the caudofemoralis (longus): that muscle acts mainly during weight support (stance phase) as an antigravity/extensor muscle, whereas the flexor action of biceps makes it more useful as a limb protractor or “swing phase” muscle used to collapse the limb and draw it forwards during weight support. However, mammals add some complexity to that non-supportive function of the biceps…

Hey mammals! Show us your biceps!

Jaguar forelimb with biceps peeking out from the other superficial muscles, and its cousin brachialis nicely visible.

Jaguar forelimb with biceps peeking out from the other superficial muscles, and its cousin brachialis nicely visible, running along the front of the forearm for a bit.

Elephant's left forelimb with the biceps labelled.

Elephant’s left forelimb with the biceps labelled.

Longitudinal slice thru the biceps of an elephant, showing the internal tendon.

Longitudinal slice thru the biceps of an elephant, showing the internal tendon that helps identify where the two bellies of the biceps fuse.

In certain mammals; the phylogenetic distribution of which is still not clear; the biceps brachii forms a key part of a passive “stay apparatus” that helps keep the forelimb upright against gravity while standing (even sleeping). The classic example is in horses but plenty of other quadrupedal mammals, especially ungulate herbivores, show evidence of similar traits:

Giraffe biceps cut away proximally to show the

Giraffe biceps cut away proximally to show the “stay apparatus” around the shoulder joint (upper right).

Zooming in on the

Zooming in on the “stay apparatus”; now in proximal view, with the biceps tendon on the left and the humeral head (showing some arthritic damage) on the right, with the groove for the biceps in between.

Hippo's humerus (upper left) and biceps muscle cut away proximally, displaying the same sort of

Hippo’s humerus (upper left) and biceps muscle cut away proximally, displaying the same sort of “stay apparatus” as in the giraffe. Again, note the stout proximal and distal tendons of the biceps. The proximal tendon fits into the groove of the humerus on the far left side of the image; becoming constrained into a narrow circular “tunnel” there. It’s neat to dissect that region because of its fascinating relationships between bone and soft tissues.

The biceps brachii, in those mammals with a stay apparatus, seems to me to have a larger tendon overall, especially around the shoulder, and that helps brace the shoulder joint from extending (retracting) too far backward, whilst also transmitting passive tension down the arm to the forearm, and bracing the elbow (as well as distal joints via other muscles and ligaments). It’s a neat adaptation whose evolution still needs to be further inspected.

Otherwise, I shouldn’t say this but the biceps is sort of boring, anatomically. Whether you’re a lizard, croc, bird or mammal, a biceps is a biceps is a biceps; more or less-ceps. But the biceps still has a clear evolutionary history and Darwin would gladly flex his biceps to raise a pint in toast to it.

So now we know a muscle better. That’s two muscles now. And that is good; be you predator or prey. Let’s shake on it!

I was greatly inspired by scenes from the global Women’s March this weekend. It was one of the more beautiful things I’ve seen lately in times that otherwise feel very dark. I write this post with some trepidation but fuelled by that inspiration. While it is nominally about women (in science and the world) it applies just about as well to many other parts of American/British, Western and global society; especially to issues of social equality. I am definitely not an expert on this topic; experts probably will see nothing new here. Some would say that means I should be silent. I feel compelled to say something, for many reasons that I feel are valid. However, I have made dumb mistakes or just been ignorant of the issues throughout my life, so I do not claim to be on a pedestal of model behaviour. But this post is not about me or anyone I personally know per se. It is about humanity and what inspires (e.g. yesterday’s marchers) and worries (e.g. a person whose surname begins with a “T”) many people, and what I have gradually learned about human nature. If it helps one person inspect and maybe change their attitudes that would be wonderful, but I may never know if that is the case, which is fine. That, anyway, is my motivation; to support what I feel is important, and to address what the post’s title refers to. Not in a smug, let’s-show-how-politically-correct-we-are way, but in a positive way, endorsing that by opening our minds and hearts we can surprise ourselves with change that improves others’ lives and our own.

Stomach-Churning Rating: reactions will vary. No pictures.

If we abstract (Western) history into a direction over time, the status quo of white (non-poor, heterosexual, religious, etc.) males has changed over recent centuries, but it remains undeniably strong. The 1950s-1960s saw considerable changes and this trend continues. As a very brief generalization, that is cause for hope for humanity. But what worries many people today is that this trend, like any in history, could reverse, and thereby do great harm to many people. This concern is not based simply on idle speculation or propaganda but on clear actions, policies and statements of some world leaders (not just the “T” guy but he is prominent). No one knows what the future holds but people can choose to act or not act; and act in person (most effective) vs. act vocally (better than silence). Yesterday’s protests were peaceful, probably even more so than the inauguration was, and society should breathe a sigh of relief for that. But it doesn’t end there.

I want to get to one of the core issues that has helped me understand – and understanding here is so vital for society to heal the frightening rifts that have developed – why people are upset. This unsettled feeling many of us experience cuts both ways: those on the right-ward side of politics also may feel that their values are threatened. Some of those values are indeed common values, such as economic inequality and concerns about terrorism or war, much as we may differ on how we react to or prioritize them. These common values give me hope. There are few values that apply to 100% of us and that means there will always be people that are unhappy; I’m not an idealist who expects utopia anytime soon. Some values will not endure the “arrow of history”, either permanently or temporarily, and that frightens people for various reasons across the political spectrum. Neo-Nazis, and those that share some beliefs with them even if they consider themselves to be very distinct from fascists, might be emboldened lately, but they have a lot of history and social momentum to contend with.

For those that are unsettled by yesterday’s marches and other recent events, for whatever reason, I ask them to think about this: try putting yourself in the shoes of one of the marchers. Step outside yourself, be curious about what their background is, and practice empathy – what is it like to be, for example, a woman at this point in history? I’m a male so I can’t wholly experience that, but I am curious and I have cultivated some skill in empathy. I want to know what it’s like being different from me. Growing up in a moderately liberal Midwestern family with three females helped me do that (plus now having my own family), and now that I am a senior(ish) leader in my field I have to think about these things on a daily basis. But I’m not perfect, either. I keep learning. I try to listen.

One way that I continually remind myself to practice is to think of “death by a thousand cuts” (good STEM example linked there) – what does it feel like to, throughout one’s life, experience what a member of the non-status quo does? In the case of a woman, what does it feel like to continually be judged based on appearance, to be treated like property, to be told you’re inferior, to be expected to obey men, to statistically have worse pay and career advancement chances, to be dismissed as inexperienced no matter what your qualifications are, and much more; all in ways that qualitatively or quantitatively are not experienced by most men. It would wear me down, and that’s what women and other disadvantaged members of society experience. The situation has improved in some areas but still is far from fair or pleasant or, simply put, far from moral and ethical. Personally, the “thousand cuts” metaphor has helped me to empathize with many people. I reflect on it regularly.

The status quo have it easier (by definition), so hearing such people tell “social justice warriors” to be silent; to endure discrimination or assault; is deeply unsettling to those that have lived their lives suffering the thousand cuts, and to those that care about them. Free speech cuts both ways, too; it may feel hard to be criticized if you get shamed for speaking out against social equality. But do centuries of history of male dominance validate that men, too, have suffered the thousand cuts? No way, man. That’s where major fracture lines in society lie – women and other people don’t get to choose that they are on those lines, and may validly feel that their power to affect what society chooses to do is weaker.

Maybe the marches yesterday inspired, you, too. Maybe this post gets you to examine your own biases? Maybe we all have inclinations that are unconsciously a bit sexist, racist, homophobic and intolerant. And yes, we need to listen to those across the political spectrum, too, and try to find common ground that can improve life for as many people as possible. To bring things back to science and this blog, that common ground needs to have a foundation of facts. Those facts are out there, and in this “post-truth” time we need to work harder to share them and establish them, which does seem to make finding a common ground harder. Nonetheless, I hold on to hopes that we can do that, much as these times often feel very grim, as if we are at a critical juncture in history (e.g. climate change!) and yet society is so fractured it cannot do the right thing.

The world is complex. I’ve over-simplified things here; an “arrow of history” is debatable and probably not inevitable in most cases (maybe better put: there are sustained directions AND repeated cycles in history; most traversing generations). Simple statements often don’t hold true across reality; science shows us that the more we learn, the more complex and nuanced the world looks, and that can be baffling or even scary. Much as we should be suspicious of simple answers like “do not question authority” or “authority is wrong”, we should consider some simple answers as useful points of departure for deeper discussions. One such simple answer is that the women’s marchers did the right thing, showing peaceful but strong solidarity against oppressive stances that threaten them. If you oppose that simple answer, can you view it from their side, though, and understand their argument through curiosity about it and empathy for their lives? Inspect your own answer. Self-doubt is something scientists learn to practice and it is a healthy life-skill too.

Can you dream another person’s dreams? Can you help people wake up from their living nightmare? It needn’t take bravery to do this. It takes honest curiosity and empathy about the world outside your own. This applies to humanity and across nature, too. I’m not brave in posting this; I have it relatively easy. I can embrace that and I can make what might seem like sacrifices, and I can enjoy the outcome; I would love to see others live a better life. Many things have to happen for humanity to draw closer together, but these are among them. Not only could more curiosity and empathy make life better for humanity, but on a personal level those traits are good for mentoring, for teamwork, for being a good colleague, and should be good for anyone you care about.

As attentive readers may know, Freezersaurus died over a month ago. We’ve been thankful for the winter’s chill that slowed the thawing process of our treasure trove of specimens while we complete the move to a temporary freezer. The gelid torch was thus being passed to the next walk-in freezer at a glacial pace– but with the glacier-scale force of Team Hutch’s collective muscles.

Stomach-Churning Rating: Hmm tough call; 6/10 if you know what it’s like to clean out a nasty freezer, 4/10 if not.

Aww. The freezer-moving team is not thrilled by the task ahead.

Aww. The freezer-moving team is not thrilled by the task ahead, and is exerting their frowning-muscles. (photo: Sophie Regnault)

Santa (Jim Usherwoodclaus) brings a bag-- of elephant feet!

Santa (Jim Usherwoodclaus) brings a bag– of elephant feet! (photo: Sophie Regnault)

Yet this week it all ends. With Crimbo’s long break ahead and an uncouth urinal smell pervading the dripping carcass of Freezersaurus, we have to clear out our little frozen ark. Some specimens have had to meet the incinerator early; others have returned to frozen limbo pending our future attention; and some are now just clean bones.

One of our many young emus that needed cleaning after thawing; here, just the right leg bones.

One of our many young emus that needed cleaning after thawing; here, just the left leg bones.

Quite a puzzle: one young emu's skeleton to reassemble in the future. Thanks to Sandy Kawano et al. for cleaning help!

Quite a puzzle: one young emu’s skeleton to reassemble in the future. Thanks to Sandy Kawano et al. for cleaning help!

Horse forelimb from an old joint range-of-motion study we did; now reduced to bones (why did I keep this frozen anyway? who knows).

Horse forelimb from an old joint range-of-motion study we did; now reduced to bones (why did I keep this frozen anyway? who knows).

So our temporary new freezer could use a name; Freezersaurus II just won’t do. In the spirit of democracy (and Yuletide), I’ll open the floor to nominations. Nothing could go wrong with populism, right 2016? Hello? Oh crap.

Last cartful of elephant feet!

Last cartful of elephant feet! (also: keen eyes may spot some gory graffiti)

Last look at Freezersaurus: Inside looking out.

Last look at Freezersaurus: Inside looking out.

Last look at Freezersaurus: outside looking in. Ice still lingering on the cow and horse legs from old XROMM studies.

Last look at Freezersaurus: outside looking in. Ice still lingering on the cow and horse legs from old XROMM studies, at the back, past the slurry of blood.

Enjoy some photos of the move, and please make freezer name suggestions in the Comments.

Our new digs, for the time being.

Our new digs, for the time being.

And, if I don’t post again in time, Happy Holidays! May the dark times not Krampus your style.

-John, Dean of the Demochilling Polarpublic of Freezevania

Let’s let Mike Ness sing us out…

UPDATE:

OK we have, via various forms of social media, these nominations for our temporary freezer’s name (I took one from each person suggesting a name;  I hope I caught them all); so let’s open it to a poll!

link:

https://polldaddy.com/poll/9610500/

[Wordpress is not showing the poll on all browsers so you may have to click the link]

(The nominations: Freezersuchus, Freezertherius, Freezopolis, Eofrigidum, Narnia and Pleistoscene)

While you’re at it, check out Anatomy To You’s new blog post: do turtles wiggle their hips and if so how much? Now we know!